1. Informed decision-making comes from a long tradition of guessing and then blaming others for inadequate results.

2. Remind people that profit is the difference between revenue and expense. This makes you look smart.

3. Most success springs from an obstacle or failure. I became a cartoonist largely because I failed in my goal of becoming a successful executive.

4. I try to manage my day by my circadian rhythms because the creativity is such an elusive thing, and I could easily just stomp over it doing my administrative stuff.

5. Some of my best friends are Venture Capitalists, but let’s face it, a hamster with Alzheimer’s could make those kind of numbers. It’s great work if you can get it.

6. When you hire that first person, then you’re a boss. You’ve got performance reviews. You’ve got complaints about not making enough money. You’ve got people who are just going to sell your story to the tabloids.

7. In fact, most people are being squeezed in their little cubicle, and their creativity is forced out elsewhere, because the company can’t use it. The company is organized to get rid of variants.

8. I had several different bosses during the early years of ‘Dilbert.’ They were all pretty sure I was mocking someone else.

9. Success is entirely accessible, even if you happen to be a huge screw-up 95 percent of the time.

10. Beware of advice about successful people and their methods. For starters, no two situations are alike. Your dreams of creating a dry-cleaning empire won’t be helped by knowing that Thomas Edison liked to take naps.

11. For most people, it’s easy to be passionate about things that are working out, and that distorts our impression of the importance of passion. I’ve been involved in several dozen business ventures over the course of my life, and each one made me excited at the start. You might even call it passion.

12. I’ve tried lots of things. The reality is, I’m excited by everything on Day 1. And if by Day X things aren’t working the way I hoped, I lose my passion. I have not seen the correlation between my passion and my success.